While the cause of deafness antigen has not yet been isolated, the success of treatment by immunosuppression has given its acceptance as a clinical entity well determined. Unfortunately the inner ear is one of the few tissues that can not be biopsied for histo and immunopathologic study. But since the first descriptions of Mc Cabe in 1979, has accumulated enough experience to not doubt their existence.
However it may give the appearance of the auditory condition, the only component of the disease. It is also possible that hearing loss is fitted to patients with classic autoimmune diseases.
The lesions may be cochlear or retrocochlear. Cochlear lesion histopathologically in autoimmune complexes can block the vessels of the stria vascularis resulting in hypoxia and ischemia. Will retrocochlear when the immune mechanism produces a demyelinating neuropathy. Complement activation leads to increased vascular damage and further tissue inflammation, such as a severe vasculitis in the internal auditory artery, ischemic necrosis and fibrosis in the inner ear.
The diagnosis of autoimmune hearing loss is essentially clinical and should be raised whenever there is a bilateral sensorineural condition, usually asymmetrical and progressive, although it may be fluctuating or even sudden.
The examination must track record of injuries or illnesses likely or certain autoimmune origin, as well as inflammatory processes that affect undiagnosed musculoskeletal, eye, kidney, gastrointestinal, cardiopulmonary, hematological, neurological or skin.
From the moment the diagnosis of this condition is usually presumptive, the aggressive anti-inflammatory and immunosuppressive approach should be evaluated in each particular case, depending on the severity of hearing loss and the presence of other elements that reaffirm and supporting the presumption .
It is essential that the therapy is started early, as it largely depends on the degree of reversibility of the lesion.
The answer, when treatment is early, often spectacular, with a total recovery.
Cure your acne with the best acne solutions
